I have acrylic nails and I don't think it interferes at all!! The one thing is I used to go through tons of different acrylic colors and now since I'm at mac I can only have black or white.. It's cool though!! I actually find it easy to put on lashes with them because I can hold them really precisely and I can use the corner of my nail to press the edges of the lashes if the glue isn't really holding that well... You know?? I think you just have to wear them and figure out if you can handle it with makeup application and whatnot.

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..Every two seconds a M.A.C eyeshadow is sold somewhere in the world..