If you use the colors everyday, I'd say the quad can last about a year or so. If you don't use them that much, then I think a palette can last a lifetime! I don't think I'll ever use up all of Sweetie Cakes, Pandamonium, Take Wing, Well Plumed, or Novel Twist Cool Eyes. I think that Smoking Eyes and Gentle Fume might be ones I'll go through though. Also theres a nice dent in most of the colors in my Holiday 06 Smoked Eyes palette.