I went to a dermatologist for the first time just about two weeks ago, and I'm so happy I went! I saw the physician's assistant, which was fine by me since they can write prescriptions, and she gave me samples and a prescription for Ziana. It's very similar to Retin A but also has an antibiotic in it, clindamycin. I've been having great results with it! My skin the first week cleared up significantly, and now the "initial breakout" is starting up, but it's not too bad. I wash my face in the morning with the Biore ice cleanser, from the Complexion Clearing line, and apply the usual SPF moisturizer and eye cream. Then at night, I use Origins Checks and Balances cleanser and apply the Ziana afterwards. The PA recommended that I don't put any other lotions on before or after applying the Ziana at night - something about them affecting how the prescription works. The only side effects I've experienced are slight dryness of my skin and a little bit of redness, which is exacerbated by the fact that it's freezing cold at the store where I work! I hope this stuff continues to work well for me - I go back to the derm in mid-October for a follow-up.